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Within their range of applicability both approaches matched
2021-08-20

Within their range of applicability, both approaches matched the phase boundaries and yields generally to within the measurement error. The approaches matched the phase compositions generally to within 11 wt% or less with the average absolute deviations listed below: One advantage of the proposed a
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br Making the BN Cox
2021-08-20

Making the BN-Cox model computationally efficient One of the challenges to applying the BN-Cox model is an exponential growth of the conditional probability tables (CPT) corresponding to the survival variables, as the number of risk factors increases [22]. When the number of risk factors is high,
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Several highly selective COX inhibitors
2021-08-20

Several highly selective COX-2 inhibitors (coxibs) have been reported and marketed [6], including celecoxib [7] and etoricoxib [8] (Fig. 1). Even though these drugs produce less ulceration than conventional NSAIDs, coxibs still produce significant gastric and cardiovascular side effects due to the d
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Within the cluster of North African populations the
2021-08-20

Within the cluster of North African populations the Sousse population sample is somewhat different from the other six populations. One has to analyze more in depth the reasons of this isolation that has been shown by other genetic studies (Fadhlaoui-Zid et al., 2015). It seems that the particular ge
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In frame exon skipping of COL A has been suspected
2021-08-20

In frame exon 41 skipping of COL6A3 has been suspected to be responsible for isolated dystonia in several human kindreds without muscular defects [94]. In order to validate their hypothesis, the authors used zebrafish to selectively knock down several exons in col6a3 and found a negative impact on m
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One possibility to differentiate between
2021-08-20

One possibility to differentiate between the two failure modes, and also to identify the corresponding characteristics of the resulting fracture surface, is a series of FNCT measurements with varying nominal (initial) stress. The dependence of the observed time to failure tf on the actual stress cha
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br Discussion The N terminal domain of DDRs has long
2021-08-19

Discussion The N-terminal domain of DDRs has long been recognized as a member of the DS superfamily (Johnson et al., 1993, Karn et al., 1993), and its role in collagen binding is understood in atomic detail (Carafoli et al., 2009, Ichikawa et al., 2007). Our crystal structure shows that the secon
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Epinephrine HCl PRRSV is a single stranded positive sense en
2021-08-19

PRRSV is a single-stranded, positive-sense enveloped RNA virus in the family Arteriviridae of the order Nidovirales (Meng et al., 1994, 1996). The PRRSV Epinephrine HCl is approximately 15 kb in length and contains eleven known open reading frames (ORFs) (Snijder et al., 2013). The 3′ end of the ge
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The concept of GPCRs and EGFRs existing as heteromers is
2021-08-19

The concept of GPCRs and EGFRs existing as heteromers is consistent with previous studies. Co-immunoprecipitation studies have shown that agonist stimulation (both AngII and EGF) promotes a multi-protein complex containing the AT1R and EGFR, however these endpoint assays were not in live cells or in
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In addition to playing important
2021-08-19

In addition to playing important roles in the immune system, EBI2 is also expressed in the XL184 of the central nervous system (CNS), namely astrocytes, and this receptor regulates astrocyte signalling, as well as astrocyte cell migration (Rutkowska et al., 2015, Rutkowska et al., 2016a). Moreover,
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mao inhibitors p as a cyclin dependent kinase
2021-08-19

p21, as a cyclin-dependent kinase inhibitor, exert significant negative regulator of proliferation, and it could be transcriptional upregulated by p53 in order to impel transient mao inhibitors arrest (Romanov et al., 2010). Using western blotting, we found that the protein expression of p21 upgrade
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A potential weakness of the present study is that
2021-08-19

A potential weakness of the present study is that it involved population controls rather than family controls, which are a better way of controlling the effects of population stratification (e.g. ethnic group differences in allele frequencies). On the other hand, general population samples do have t
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jlk mg The present study was set to characterise the DNMT
2021-08-19

The present study was set to characterise the DNMT gene orthologs and describe the expression patterns of these genes during seed development in natural diploid apomict B. divaricarpa and diploid sexual B. stricta. Material and methods Results The B. stricta genome v1.2, was sequenced and ass
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br Results br Discussion In addition to contributing
2021-08-19

Results Discussion In addition to contributing to amino L-703,664 succinate and lipid biosynthesis, mitochondrial metabolism affects nucleotide biosynthesis. Indeed, many components that contribute to both pyrimidine and purine bases are derived directly or indirectly from mitochondria. Beside
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Kuo et al Have shown that DAPK function
2021-08-19

Kuo et al. (2006) Have shown that DAPK1 function in inhibiting microtubule (MT) assembly is through the activation of microtubule affinity-regulating kinases (MARK)/PAR-1 family kinases MARK1/2, which destabilize MT by phosphorylating tau and related MAP2/4. This relation with DAPK1 has demonstrated
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