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br Suggestions in the context of World Heritage
2018-11-12
Suggestions in the context of World Heritage The bid for the Grand Canal to be included in the World Heritage List is not the only objective, but also it\'s conservation and management. The current situation shows that the different roles of the Grand Canal determine it\'s multi-department manage
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Unique address for each building component The very essence
2018-11-12
Unique address for each building component The very essence for the designer software I am interested in is to see all constructs (buildings, installations, environments) as in principle dynamic structures, consisting of a large set of thousands of programmable components. Programmable components a
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We ignore the names of
2018-11-12
We ignore the names of the owners and the identity of the tenants of the two domus. However, according to the location at the centre of the Urbs (city) near the Imperial Fora and according to their dimensions (over 1000m2) and plan, typical of important late Roman domus, we may suppose that they wer
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As a designated Level I trauma center providing care for
2018-11-12
As a designated Level I trauma center providing care for severely injured patients, our hospital infrastructure includes a trauma and emergency surgery division under the department of surgery. Trauma surgeons are responsible for all injured patients (major and minor trauma) presenting to the ER and
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Introduction The role of a surgical
2018-11-12
Introduction The role of a surgical margin in surgical oncology has always been discussed with regard to the tumor recurrence and survival rate in gastrointestinal cancer surgery. Previous reports have suggested that extensive operation with a wide resection margin and extensive phosphodiesterase i
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Forehead osteomata can be removed by burring
2018-11-12
Forehead osteomata can be removed by burring or osteotome chiseling. Comparing these two methods, bone burring is not an efficient method for removing osteomata. It also increases the risk of soft tissue injury or a depressed bony surface. Removal of an osteoma by a curved osteotome is, however, bot
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cholecystokinin receptor br Key problems that need to be res
2018-11-12
Key problems that need to be resolved to understand the relationship between foods and health In term of the relationship between foods and health, the following four key problems have to be addressed: (1) Undernutrition causes nutrition deficiency, and overnutrition leads to obesity, hypertensio
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AUY922 br Materials and methods br Data analysis All results
2018-11-12
Materials and methods Data analysis All results are presented as means±SEM. Comparisons between groups were analyzed using t-tests (two-sided). Differences with p values of less than 0.05 were considered significant. The p values were corrected for multiple testing procedures and to control ty
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LDS BBs were found to
2018-11-12
LDS BBs were found to respond to ET-1 stimulation with a decrease in cell shortening. Furthermore, our findings that BQ123, but not BQ3020, blocked the negative shortening response to ET-1 are consistent with those of Izumi and co-workers (Izumi et al., 2000) and indicate an ETA receptor-mediated ef
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Regarding JNK phosphorylation levels were either moderately
2018-11-12
Regarding JNK, phosphorylation levels were either moderately (for JNK 1) or significantly increased (for JNK 2/3) at 5μM SB203580 compared to DMSO controls; these effects were further pronounced at 30μM (Figs. 5 A–B, schema in Figs. 6 C–D). This suggests a concentration-dependent activation of JNK
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We derived ESC lines from
2018-11-12
We derived ESC lines from blastocysts of the double transgenic mouse line Mlc2v-Cre; Rosa26-Yfp, in which Cre and Yfp are specifically knocked into the Mlc2v and Rosa26 gene loci, respectively. Mlc2v-Cre-mediated removal of a stop sequence in the Rosa26-YFP reporter line results in expression of YFP
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Most published protocols for the
2018-11-12
Most published protocols for the endothelial differentiation of hESCs employ stromal co-culture (Boyd et al., 2007; Vodyanik et al., 2005) or utilise media with undefined or animal derived components such as serum, albumin fractionated from bovine serum, conditioned media or extracellular matrices (
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Both Brat and Mei P belong to the Trim
2018-11-12
Both Brat and Mei-P26 belong to the Trim-NHL family of proteins, which have conserved functions in stem cell lineages from C. elegans to mouse (for review, see Wulczyn et al., 2010). Proteins within this family are potential E3 ubiquitin ligases and can act by either activating or antagonizing the m
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In hematopoietic systems individual blood progenitor
2018-11-12
In hematopoietic systems, individual blood progenitor ionomycin each appear to have their own proliferation program with “self-replication potential.” Identification of the self-replication factors in lineage blood progenitors should enable immortalization of the cells. With that in mind, we have b
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Modulation of GASZ by ectopic overexpression or by RNA
2018-11-12
Modulation of GASZ by ectopic overexpression or by RNA interference in ESCs affected several key germ cell markers, such as Oct4, Dazl, Mvh, Miwi, and Mili, which may in turn contribute to the altered PGC or EGC derivation from differentiated EBs. Since GASZ is localized in the intermitochondria cem
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