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Our patient presented with sudden
2018-11-02
Our patient presented with sudden onset of scrotal enlargement and irritability. Although these symptoms were not usual manifestations of testicular torsion, they were compatible with those of a 3-month-old, since young infants may show obscure clinical features. A cystic testicular lesion is often
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br Introduction br Case report A year old
2018-11-02
Introduction Case report A 10-year-old girl, 28 kg in weight and 142 cm in height, was scheduled for surgical excision of a left atrial mass diagnosed by transthoracic echocardiography. Her physical examination was unremarkable. A written preoperative consent for anesthesia including CVC and t
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br Conclusion Based on the fluorescence intensity changes
2018-11-02
Conclusion Based on the fluorescence intensity changes of p65 in this study, LPS at concentration of 0.01, 0.1 and 10μg/mL can significantly activate NF-κB signaling pathway (Pthe (S)-Crizotinib of p65. The maximum express was achieved at a LPS concentration of 1μg/mL and treatment duration of 3
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br Integrin Expression in Human Stem
2018-11-02
Integrin Expression in Human Stem Cells Integrin expression in human embryonic stem p-Cresyl sulfate and selected adult stem cell types is summarised in Table 2. We define here the known expression profiles of integrins on human stem cells of four different types: embryonic, mesenchymal, haematop
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br Author contribution The following are the supplementary d
2018-11-02
Author contribution The following are the supplementary data related to this article. Acknowledgments We thank Catherine Bresse for her valuable assistance in the statistical analysis. This work was supported by the CIRM grant # RL1-00636-1. Introduction The capacity of human embryonic st
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Using the optimized operating conditions we
2018-11-02
Using the optimized operating conditions we demonstrate serial passaging and expansion of two integration-free hiPSC lines in completely defined xeno-free media in 100-ml bioreactors. The Talabostat mesylate exhibited homogeneous aggregate formation, steady expansion in their pluripotent state, and
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Introduction A key question in cardiovascular biology is
2018-11-02
Introduction A key question in cardiovascular biology is to what degree the heart is able to regenerate after tissue damage from either cardiac stem cells or cardiomyocyte division. Cardiovascular disease including myocardial infarct is currently one of the leading causes of death worldwide, and th
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br Conclusions Whilst it is clear that
2018-11-02
Conclusions Whilst it is clear that RNA-binding proteins play crucial roles in regulating oogenesis, understanding the functions of these proteins relies on identifying the RNA targets they bind and regulate. Given the relative promiscuity of RNA-binding proteins, it seems likely that the fertili
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Using both standard RNA seq and
2018-11-02
Using both standard RNA-seq and RNA-seq topoisomerase inhibitors analysis, we identified UPF1-regulated transcripts that are good candidates to be direct NMD targets in hESCs. There was considerable overlap between these candidate NMD target transcripts expressed in hESCs with previously identified
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br Experimental Procedures br Author Contributions br
2018-11-02
Experimental Procedures Author Contributions Acknowledgments The authors acknowledge Hope Campbell at Blood Center of Wisconsin for performing FACS sorting. This work was supported by gifts from the Marcus Family, the Phoebe R. and John D. Lewis Foundation, the Sophia Wolf Quadracci Memoria
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The activation of Notch has been found
2018-11-02
The activation of Notch1 has been found to contribute to the invasion and metastasis of cancer via the EMT. In addition, Saad et al. (2010) showed that the overexpression of NOTCH1 induces the expression of SNAIL. In the present study, after GSI treatment the expression of NOTCH1, SNAIL1, and SNAIL2
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Delivery of Cas protein in
2018-11-02
Delivery of Cas9 protein in an RNP complex with the sgRNA avoids the need for in vivo transcription and translation. Moreover, this approach yields high expression shortly after nucleofection, followed by rapid degradation, thereby facilitating efficient gene editing while minimizing off-target rate
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A perceptron network that had
2018-11-02
A perceptron network that had previously proved to be the most sensitive to new complementary data about the model was used in the experiments. The number of endothelin receptor antagonist in the network was chosen to equal 20 (n = 20); the data used was on the correspondence between the sought-for
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The present work reports for
2018-11-02
The present work reports for the first time the synthesis of Ca5(PO4)3Cl:Eu2+ phosphor via the Pechini (citrate gel) method and the investigation of its photoluminescent properties. Experimental For synthesis of Eu2+ activated chlorapatite phosphor Ca5(PO4)3Cl stoichiometric amount of the precur
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Birinapant cost In this paper we used
2018-11-02
In this paper, we used a variation of the classical theory considering shells to be surfaces with material normals, constructed on the basis of Lagrangian mechanics [11–14]. Different applications of this theory have been described in Refs. [15–17]. The second part of the paper deals with static st
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