• The conventional cutoff for small for gestational age is bas

  2019-06-10

  

  The conventional cutoff for small for gestational age is based on birthweight, which is suitable for infants born at term but is far less appropriate for those born preterm. Preterm birth is itself pathological, and ultrasound-based estimates of fetal weight show that infants born preterm are much s

• Repurposing use of approved drugs for new indications

  2019-06-10

  

  Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o

• Pero en los a os noventa como refere

  2019-06-10

  

  Pero en los años noventa, como refere Brito, al inventariarse los resultados de la estrategia de desarrollo y de las reformas adelantadas en la década anterior, es decir ante una revisión “crítica” del “Consenso de Washington”, fue evidente que los costos en términos de inequidad y dualización socia

• A Irmandade da Santa Casa de

  2019-06-10

  

  A Irmandade da Santa Casa de Misericórdia de São Paulo é formada por membros da sociedade que passam direct thrombin inhibitors ser chamados de Irmãos. Desses, são escolhidos os que compõem a Mesa Administrativa, a qual escolhe a diretoria, nomeados como provedor e superintendente. Em geral, são pro

• The GCT usually involves a cladding

  2019-06-10

  

  The GCT usually involves a cladding that consisted of reactive bone and fibrosis, with a distinct boundary surrounded by soft tissue. Nevertheless, the active cladding is very thin among patients with severe invasiveness, including tumors that extend directly in into the muscle and fat, or other sig

• br Treatment and follow up recommendations for patients

  2019-06-10

  

  Treatment and follow-up recommendations for patients receiving aromatase inhibitors Conclusions and future directions It is evident that, in addition to BMD, clinical risk factors can greatly influence fracture risk. In addition to morbidity and mortality, fractures are associated with high he

• The Zika virus epidemic is spreading countries are now

  2019-06-06

  

  The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil

• To facilitate WHO s goals it is important to assess

  2019-06-06

  

  To facilitate WHO\'s goals, it hydroxylase is important to assess the cost-effectiveness of interventions that incorporate emerging technologies for case detection, treatment, and vector control in the context of economic constraints and logistical barriers. In an elegant modelling study in , Simon

• In terms of outcome based

  2019-06-06

  

  In terms of outcome-based assessments, we analyzed the primary outcomes in both the 7-day and in-hospital mortality, to evaluate further whether the cause of death would be related to acute illness or chronic comorbidities, and furthermore to ensure care quality in both units. Illness severity and t

• Desde su conceptuaci n inicial en por Gustavo

  2019-06-06

  

  Desde su conceptuación inicial en 1968, por Gustavo Gutiérrez Merino —considerado “padre” y uno de los más trascendentes exponentes de esta corriente— la tl surgió como una reflexión posterior Pyrrolidinedithiocarbamate ammonium un primer momento, consistente en la realidad misma de diversos sectore

• The management of PEComa follows the

  2019-06-06

  

  The management of PEComa follows the same treatment principles as other subtypes of soft tissue sarcoma. Surgical resection remains the primary treatment modality. There is no consensus on the administration of adjuvant treatment. Other treatment options, including chemotherapy and radiotherapy, hav

• The tumor microenvironment is enriched with EMVs

  2019-06-06

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• Aggressive osteoblastoma is characterized by epithelioid

  2019-06-06

  

  Aggressive osteoblastoma is characterized by epithelioid osteoblasts that are, two to three times larger than conventional osteoblasts, and have abundant eosinophilic cytoplasm, large vesicular eccentric round to oval nuclei with prominent nucleoli. Usually there are rare or absence of mitoses and i

• A number of studies have shown that

  2019-06-06

  

  A number of studies have shown that zoledronic Erismodegib has the ability to potentiate effects of anti-tumor agents such as doxorubicin [21] or everolimus [22]. In a recent paper the combination of chemotherapy with a single infusion of 4mg zoledronic acid in patients with breast cancer was shown

• We conducted a retrospective analysis

  2019-06-06

  

  We conducted a retrospective analysis to compare a BMD-alone strategy, versus BMD+FRAX® and BMD+FRAX®+TBS screening strategies. To our knowledge, this constitutes the first study to assess the relative contributions of FRAX® and TBS. In our cohort, FRAX®+BMD identified 9 (9%) additional patients at

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