• Long marginalised as a disorder confined to

  2019-05-07

  

  Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th

• The lack of a single identified correlate of protection

  2019-05-07

  

  The lack of a single identified correlate of protection for LAIV should not deter future immunogenicity studies in resource-limited settings, especially using systems vaccinology approaches designed to dissect the complex interplay of innate and adaptive pathways following vaccination. John C Victor

• Calkins et al demonstrated that

  2019-05-07

  

  Calkins et al. demonstrated that volume loading has a greater electrophysiological significance under pathologic conditions such as chronic infarction [8]. Some vasodilators can counteract such electrophysiological changes and suppresses VT. Captopril prolonged the ventricular refractory cycloastrag

• br Study limitations br Introduction The spread of basic

  2019-05-07

  

  Study limitations Introduction The spread of basic life support (BLS), including use of automated external defibrillators in the general public, may increase the chance of survival from sudden cardiac death (SCD). Survivors usually have underlying cardiac diseases, such as coronary artery dise

• Finally MM patients have accelerated bone loss when compared

  2019-05-07

  

  Finally, MM patients have accelerated bone loss when compared to age-matched controls. Bone mineral density is decreased in patients with MM as well as in patients with monoclonal gammopathy of undetermined significance (MGUS) [19,20], a clinically benign condition defined by a low level of monoclon

• br Methods br Results br Discussion Bisphosphonates reduce s

  2019-05-07

  

  Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve

• entacapone br Conclusions br Acknowledgements This

  2019-05-07

  

  Conclusions Acknowledgements This work was supported by Bloodwise, the International Myeloma Foundation and a Marie Curie Career Integration Grant from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [294160]. The osteoblast in normal bone physiology

• br Alternans and arrhythmogenesis in different clinical cond

  2019-05-06

  

  Alternans and arrhythmogenesis in different clinical conditions APD alternans, whether spatially concordant or discordant, can produce arrhythmias. For example, spatially concordant alternans themselves can produce 2:1 conduction block, thereby initiating re-entry [48]. Nevertheless, discordant a

• Hay que remontar a la Guerra Civil

  2019-05-06

  

  Hay que remontar CX5461 la Guerra Civil española que movilizó a los poetas hispanoamericanos de una manera mucho más urgente que la Segunda Guerra Mundial, para hallar el origen de los lazos de Octavio Paz con Chile. En 1937 Octavio Paz recibió una invitación para participar en el Congreso Internaci

• O quilombo caracterizado como uma associa

  2019-05-06

  

  O quilombo é caracterizado como uma associação guerreira aberta, sem distinção de linhagens e transcultural. A transculturalidade vem das contribuições de povos distintos, com destaque para os imbangala. No ritual de iniciação dos imbangala, eletriptan Supplier circuncisão representava o rito de pas

• br Methods br Results A total of

  2019-05-06

  

  Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer

• Upon examining his previous hospital records from years

  2019-05-06

  

  Upon examining his previous hospital records from 4 years prior, we found that he was diagnosed with acute heart failure at the second hospitalization 1 week after catheter ablation for atrial fibrillation. His symptoms and chest radiographic findings had improved by standard therapy for heart failu

• br Introduction Liver fibrosis cirrhosis is a global

  2019-05-06

  

  Introduction Liver fibrosis/cirrhosis is a global health problem that leads to morbidity and mortality. Alcohol abuse is one of the most common causes of liver fibrosis/cirrhosis in western developed countries and accounts for more than 50% of cirrhosis cases. Alcoholic liver fibrosis is characte

• order ha peptide In the past three decades

  2019-05-06

  

  In the past three decades, along with rapid economic growth in China, there has been a striking increase in alcohol consumption, greater than in most other parts of the world (). Although the order ha peptide drinking level in China used to be far lower than in many high-income and middle-income co

• br Bilbao en el cruce

  2019-05-06

  

  Bilbao, en el cruce entre anticolonialismo y socialismo de las periferias Como adelantamos arriba, el presente artículo reconstruye una etapa poco conocida de la vida de este autor sorprendente. El acercamiento que presentamos trata de reconstruir los contextos intelectuales del exilio parisino d

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