• Accumulating literature has showed MSCs and

  2019-04-22

  

  Accumulating literature has showed MSCs and HSCs may be beneficial for CD patients. We searched all studies available to evaluate clinical efficacy and safety of stem RGDfK in severe refractory CD. Located in bone marrow, HSCs can give rise to all blood cells and transplanted HSCs can reconstitute t

• Severe ECG abnormality associated with systolic dysfunction

  2019-04-22

  

  Severe ECG abnormality associated with systolic dysfunction of our DM1 patients. Some degree of electro-mechanical correlation has been demonstrated in several previous studies on DM1 subjects. DM1 patients with prolonged PR or QRS intervals are at four-times higher risk to develop LV systolic dysfu

• El autor otra vez se sirve de

  2019-04-20

  

  El autor, otra vez, se sirve de Chucho Hegel y su contradiscurso para poner de manifiesto los caminos posibles de la subjetividad “negra” frente Lomustine las interpelaciones externas. Como contracara del Profesor, Chucho Hegel, que ha tenido el mismo inicio intelectual del protagonista, logró trasc

• br Conflict of interest br Introduction A

  2019-04-20

  

  Conflict of interest Introduction A large number of recent reports suggest that early repolarization (ER) and J waves are associated with the occurrence of ventricular fibrillation (VF) [1–4]. In particular, the presence of J waves in global leads, including the inferolateral leads, is thought

• br Discussion It is generally

  2019-04-20

  

  Discussion It is generally known that primary CNS melanomas are rare and difficult to diagnose prior to biopsy. According to tumor melanin content, four subtypes of malignant intracranial melanoma have been proposed, associated with different MRI image presentations. These subtypes are: 1) melano

• pleasant dream In the phase AZURE trial women were randomly

  2019-04-20

  

  In the phase 3 AZURE trial, 3360 women were randomly assigned to receive standard adjuvant systemic treatment alone (control group) or with 4mg intravenous zoledronic pleasant dream every 3–4 weeks for 6 doses, then every 3 months for 8 doses, followed by every 6 months for 5 doses, for a total of

• In addition evidence of similar resting

  2019-04-20

  

  In addition, evidence of similar resting HR׳s before exercise in the patients and in the controls implies similar autonomic activity at rest during the daytime in both groups of subjects. In contrast, previous studies have reported changes in the nocturnal HR of BrS patients [3,28]. The discrepancy

• Competing pressures for resources across sectors however mea

  2019-04-20

  

  Competing pressures for resources across sectors, however, mean that increasing the proportion of resources for health will be difficult. Efficiency gains in the health sector could help to make the case for more investment. Countries need to tackle major sources of inefficiency by doing more of the

• Having to seek various approvals with no communication betwe

  2019-04-20

  

  Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen

• Baseline WBC count and baseline measures of hepatic

  2019-04-20

  

  Baseline WBC count and baseline measures of hepatic and renal function for responders and nonresponders are shown in Table 1. No relationship was evident between responders to decitabine or treatment choice and baseline WBC counts, or between responders and baseline measures of hepatic function (ALT

• br Discussion A familial platelet disorder with

  2019-04-20

  

  Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).

• Bacterial LPS stimulates monocytes and tissue macrophages

  2019-04-19

  

  Bacterial LPS stimulates monocytes and tissue macrophages to release TNF-α and IL-1, which then stimulate secondary response cytokines, including IL-6. In addition to hematopoietic cells, IL-6 is synthesized by many different types of nonhematopoietic cells, including endothelium, lasting for an ext

• br Discussion Early repolarization is

  2019-04-19

  

  Discussion Early repolarization is a common ECG characteristic. Its reported prevalence is 6–25% of the general population, and is particularly common in athletes [2,3,11,12]. It is now recognized that a small fraction of people with early repolarization on their ECGs develop lethal tachyarrhythm

• br Remote technologies The platforms available

  2019-04-19

  

  Remote technologies The platforms available for remote monitoring of ICDs differ. Wand-based (“inductive”) systems require patient-driven downloads relayed via telephone connections to tracking facilities [4,5]. These are becoming obsolete. This is because they demand coordination with a device c

• A year old man was hospitalized following a first syncope

  2019-04-19

  

  A 36-year-old man was hospitalized following a first syncope attack while awake at night. No history of sudden death was reported in his family. On arrival, his consciousness was clear and his vital signs were stable. An electrocardiogram (ECG) showed sinus rhythm with ST-segment elevations and J wa

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