• This issue of Sleep Science contains two

  2018-11-13

  

  This issue of Sleep Science contains two excellent review articles by Garcia-Rill and his colleagues examining the role of reticular activating system, especially the pedunculopontine (PPT) nucleus, in the pathophysiology of insomnia, schizophrenia, and other neuropsychiatric disorders . The PPT nuc

• In this scenario the relationship between exhausting physica

  2018-11-13

  

  In this scenario, the relationship between exhausting physical effort and musculoskeletal pain may be one of the possible explanations for the findings concerning predictors of risk for sleep disturbances among the workers studied. This is particularly true for rubber tappers, providing an intriguin

• br Conclusions A new deflection shape function that predicts

  2018-11-13

  

  Conclusions A new deflection shape function that predicts the deflection profiles of CMUTs with rectangular membranes has been proposed. It is established to accurately describe the deformations of CMUT membranes with a wide range of geometry dimensions and loading conditions. The predictions of

• br Introduction Immunosensors are a specific type of biosens

  2018-11-13

  

  Introduction Immunosensors are a specific type of biosensors and can be defined as compact analytical devices that yield measurable signals in response to specific antibody–antigen interactions. A large number of immunosensors have been developed using different kinds of transducers that exploit

• br V Conclusiones resultados pol ticos y

  2018-11-13

  

  V. Conclusiones: resultados políticos y económicos de las políticas de austeridad La mayoría de los estados europeos, como tuvimos oportunidad de ver en el presente trabajo, se endeudaron como consecuencia de los programas de rescate y de la disminución de ingresos tributarios que siguieron purch

• El tema ambiental es igual de complejo debido

  2018-11-13

  

  El tema ambiental es igual de complejo, debido al alto crecimiento económico que ha registrado China, la demanda de bienes y servicios ambientales ha sido intensiva al igual que la generación de residuos y desechos. Lo cual afecta no sólo al territorio chino sino al resto del mundo ya que los países

• br Acknowledgement The authors Andrei G Simonassi and Ronald

  2018-11-13

  

  Acknowledgement The authors Andrei G Simonassi and Ronaldo A. Arraes thank the financial support from CNPq. Introduction In recent decades, surveys were published seeking explanations for an empirical verification of Zipf\'s law. Among the most important are the works of Rosen and Resnick (19

• It is also worth noting

  2018-11-13

  

  It is also worth noting that the current relevance of cardinality-constrained portfolios is controversial. The main reason is straightforward: with the advent of new financial instruments such as exchange traded funds (ETF), nowadays investors can easily buy or sell a benchmark portfolio by investin

• dihydroergotamine As empirical research revealed that

  2018-11-13

  

  As empirical research revealed that budget institutions do affect the budget result of the government and its fiscal policy, it is essential to assess the impact of these institutions on the Brazilian budget performance, a topic, to our knowledge, underexplored in the Brazilian literature. Thereby,

• This paper investigates the evolution of the Brazil

  2018-11-13

  

  This paper investigates the evolution of the Brazil-EU bilateral trade in the period 2002–2012 and identifies trading opportunities resulting from a trade agreement of Brazil with the EU. The paper employs a computable general equilibrium model, using the 8th version of the standard Global Trade Ana

• Menezes et al also test the median voter model

  2018-11-13

  

  Menezes et al. (2011) also test the median voter model for the Brazilian municipalities and find evidence that it seems to be valid. They estimate the demand for local public services in order to obtain a measure of misperception of candidates to reelection regarding the median local demand. The exp

• Geneticists from Guangzhou China recently shocked the scient

  2018-11-13

  

  Geneticists from Guangzhou, China recently shocked the scientific community by publishing what appears to be the first attempt at using CRISPR–Cas9 genomic-editing technology to modify disease-associated DNAs from human embryos. The article appeared in the May 2015 issue of . Despite the enormous

• We have developed an in vivo model

  2018-11-13

  

  We have developed an in vivo model in which BALB/c mice synthesize DNRAbs following immunization with a configuration of the consensus sequence multimerized on a polylysine backbone (termed MAP-DWEYS), while BALB/c mice immunized with the polylysine backbone alone (MAP-core) do not (Kowal et al., 20

• Clinically a number of observations indicate that

  2018-11-13

  

  Clinically, a number of observations indicate that PES may have functional implications beyond the eye (Bettis et al., 2014; Katsi et al., 2013; Tarkkanen et al., 2008), although opinion is divided with regards to its significance (Andrikopoulos et al., 2014; Gonen et al., 2013; Hietanen et al., 200

• br Introduction Sickle cell disease SCD

  2018-11-13

  

  Introduction Sickle-cell disease (SCD) is considered a major global public health problem (Serjeant, 2014). There are approximately 250,000 births annually (Hannemann et al., 2011). Africa, bears the highest burden of the disease (Makani et al., 2013). However many cases occur in the United State

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