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The presented hMOs have a great
2018-10-24
The presented hMOs have a great potential to be used for in vitro modeling of diseases that strongly affect the human midbrain, particularly PD (Michel et al., 2016). Patient-specific hMOs might reveal specific phenotypes that are not abundant in 2D cultures and therefore may be used for mechanistic
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br The configuration of the system for
2018-10-24
The configuration of the system for photochemical reaction imaging The system is placed in a compact case that is effectively an intraoral camera with a built-in emitter. The camera field of view at a working distance from the object (about 15 mm) is 1 cm2. The construction of the system provides
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is the neutron energy that corresponds to exact Bragg condit
2018-10-24
is the neutron elastase inhibitor that corresponds to exact Bragg condition. The presence of a reflected wave with the amplitude equal to 1/ΔB leads to localization of neutron density in crystal on(or between) reflecting planes depending on the sign of ΔB: The concentration of neutron density in
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Kohonen s network training takes place in two stages
2018-10-24
Kohonen\'s network training takes place in two stages [9]. First, the distances from the training samples to each CE (neuron) are calculated by the formula [12]: where is the weighting coefficient linking the input vector to the cluster lenvatinib j. The values are transmitted to the competitive t
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br Acknowledgement br Introduction Evidence has long been ac
2018-10-24
Acknowledgement Introduction Evidence has long been accumulating about the association between social relationships and health and well-being at all ages (Cornwell & Waite, 2009; House, Landis, & Umberson, 1988; Kawachi & Berkman, 2001; Umberson, Crosnoe, & Reczek, 2010). Among life\'s most in
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Klemperer follows up and notes that switching costs are quit
2018-10-23
Klemperer (1995) follows up and notes that switching costs are quite common and can lead to important consequences, such as welfare losses similar to those observed in an oligopoly and barriers to new entrants. Padilla (1992) develops a model in which ex ante identical firms have ex post asymmetric
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A significant challenge for developing vaccines against RV i
2018-10-23
A significant challenge for developing vaccines against RV is that well over 150 strains of RV have been identified. These strains belong to three genetically related groups; RV-A, B, and C. Recent investigations indicate that some strains may be more likely to provoke an methylergometrine cost atta
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Disclosure br Acknowledgments br A critical knowledge gap in
2018-10-23
Disclosure Acknowledgments A critical knowledge gap in the field of HIV cure research is how best to measure the persistence of replication-competent HIV in the form of intact but latent proviruses. One approach to curing HIV is to eradicate all replication-competent HIV from an individual. It
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estrogen receptors We characterized structural disease load
2018-10-23
We characterized structural disease load using volumetric measures of the caudate, putamen, global gray and global white matter that show sensitivity towards HD-related changes (Tabrizi et al., 2012). These structural markers of disease load were included in a systematic examination of both estrogen
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The colon normally accounts for a small portion about of
2018-10-23
The colon normally accounts for a small portion, about 5%, of total K elimination, whereas the kidneys account for the remaining 95%. The colon, however, can become a significant site of K excretion when renal function decreases markedly. Similar to renal adaptive changes, colonic adaptive changes t
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Our data strengthen and reinforce the relationship between r
2018-10-23
Our data strengthen and reinforce the relationship between renal function and TTR (Kleinow et al., 2011; Kooiman et al., 2014). One study derived from a cohort of anticoagulated AF patients found that patients with moderate and severe CKD had higher TTR than patients with normal renal function, alth
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order GSK-3 Inhibitor IX In order to overcome these problems
2018-10-23
In order to overcome these problems, we have developed an Internet-based e-learning system which is in English, and which is available anywhere in the world, and at any time of the day, so that clinicians worldwide can learn how to detect EGC (Yao, 2013). Recently, advanced imaging endoscopy techniq
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calcium channel blockers Lung cancer is the most common canc
2018-10-23
Lung cancer is the most common cancer in US and worldwide (Centers for Disease Control and Prevention and National Center for Health Statistics, 2013; American Cancer Society, 2014), and the survival rate is low (Howlader et al., 2013). Most cases (90%) of lung cancer are attributable to smoking (Ge
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It could be argued that
2018-10-23
It could be argued that the lack of association between pre-diagnostic Treg/tTL ratios and CVD risk in the present study is due to the fact that plaques represent a different immunological compartment than blood (Grivel et al., 2011), and it remains to be determined whether Treg levels in blood adeq
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To reveal the molecular mechanism of MeCP
2018-10-23
To reveal the molecular mechanism of MeCP2 regulation, we performed a combination of microarray analysis and ChIP-Seq, through which we identified FOXF1 and MYOD1 as MeCP2 targeting genes. We confirmed that MeCP2 binds to the methylated CpG islands in the promoter regions of both genes, leading to d
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